| Overview |
| bsm-63043r-biotin-100ul |
| Cadherin Recombinant Antibody, Biotin Conjugated |
| WB, IHC-P |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Cadherin |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| Cell membrane |
| Cadherin;CDH3;CDHP;Cadherin-1;Cadherin-2;Cadherin-3;Cadherin-4;Cadherin-5;CAM 120/80;CD144;CD324;CD325;Cdh4;CDH5;CDHE;CDHN;E-cadherin;N-cadherin;NCAD;Neural cadherin;P-cadherin;Uvomorulin;Vascular endothelial cadherin |
| Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
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