| Overview |
| bsm-63003r-apc-100ul |
| Thioredoxin Recombinant Monoclonal Antibody, APC Conjugated |
| WB, IF(ICC) |
| Human |
| Specifications |
| APC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Thioredoxin |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7295 |
| P10599 |
| Cytoplasm, Nucleus, Secreted |
| TXN; ADF; ATL-derived factor; SASP; Thioredoxin; TRX1; Thioredoxin delta 3; TRX; TXN delta 3; TRDX. |
| Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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