| Overview |
| bsm-63001r-100ul |
| Phospho-TRIM28 (Ser824) Recombinant Antibody |
| WB, IP |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TIF1 beta around the phosphorylation site of S824 |
| Ser824 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 10155 |
| Q13263 |
| Nucleus |
| KAP 1; KRAB associated protein 1; KRIP1; RNF96; TF1B; TIF1 beta; TIF1B; Trim28; Tripartite motif containing 28. |
| Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |
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