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Nesprin 3 Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-62987r-100ul
Product Name Nesprin 3 Monoclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Nesprin 3
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 161176
Swiss Prot Q6ZMZ3
Subcellular location Nucleus
Synonyms C14orf49; Nesp3; Nesprin 3; NET53; SYNE3.
Background As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
Application Dilution
WB :1:1000-1:2000