Overview |
bsm-62940r-cy3-100ul |
Phospho-POLR2A (Ser5) Recombinant Monoclonal Antibody, Cy3 Conjugated |
WB, FCM, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human POLR2A around the phosphorylation site of S5 |
Ser5 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5430 |
P24928 |
Nucleus |
POLR2A; POLR2; RNA polymerase II CTD repeat YSPTSPS. |
During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |