Overview |
bsm-62931r-biotin-100ul |
PIAS1/2 Recombinant Monoclonal Antibody, Biotin Conjugated |
WB, IHC-P, IHC-F, IP |
Human, Mouse, Rat |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human PIAS1 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
8554 |
O75925,O75928 |
Cytoplasm, Nucleus |
PIAS1; PIAS2. |
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IP |
1-2ug |