Overview |
bsm-62903r-100ul |
MAPKAP Kinase 2 Monoclonal Antibody |
WB, IP |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human MK2 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
9261 |
P49137 |
Cytoplasm, Nucleus |
MAPKAP K2; MAPKAP kinase 2; MAPKAPK 2; MAPKAPK2; Mitogen activated protein kinase activated protein kinase 2; MK 2. |
Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X2-S, where Hyd is a large hydrophobic residue. |
Application Dilution |
WB |
:1:1000-1:2000 |
IP |
IP:1:20-1:50 |