Phospho-LRP6 (Ser1490) Monoclonal Antibody

Overview
Catalog #	bsm-62889r-100ul
Product Name	Phospho-LRP6 (Ser1490) Monoclonal Antibody
Applications	WB
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490
Modification Site	Ser1490
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	4040
Swiss Prot	O75581
Subcellular location	Cytoplasm, Cell membrane
Synonyms	Low-density lipoprotein receptor-related protein 7.
Background	Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Application Dilution
WB	:1:1000-1:2000