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PICALM Recombinant Monoclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-62870r-pe-cy5-100ul
Product Name PICALM Recombinant Monoclonal Antibody, PE-Cy5 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PICALM
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8301
Swiss Prot Q13492
Subcellular location Cytoplasm, Cell membrane
Synonyms CALM; CLTH; LAP; PICALM.
Background Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly.
Application Dilution
WB 1:300-5000