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PICALM Recombinant Monoclonal Antibody, PE Conjugated

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-62870r-pe-100ul
Product Name PICALM Recombinant Monoclonal Antibody, PE Conjugated
Applications WB, IF(ICC)
Reactivity Human
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PICALM
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8301
Swiss Prot Q13492
Subcellular location Cytoplasm, Cell membrane
Synonyms CALM; CLTH; LAP; PICALM.
Background Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200