HN1 Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62795r-100ul |
| Product Name | HN1 Monoclonal Antibody |
| Applications | WB, FCM |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human JPT1 |
| Clonality | Monoclonal |
| Clone # | Recombinant |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 51155 |
| Swiss Prot | Q9UK76 |
| Subcellular location | Nucleus |
| Synonyms | ARM2; HN1; HN1A. |
| Background | Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. |
| Application Dilution | |
| WB | :1:1000-1:2000 |
| FCM | FCM:1:20-1:100 |
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