Overview |
bsm-62783r-100ul |
RIP2 Monoclonal Antibody |
WB |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human RIP 2 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
8767 |
O43353 |
Cytoplasm |
CARD carrying kinase; CARD3; CARDIAK; CCK; CLARP kinase; GIG30; Growth inhibiting gene 30; Receptor interacting protein 2; RICK; RIP 2; Ripk2; TNFRSF. |
Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments. |
Application Dilution |
WB |
:1:1000-1:2000 |