Overview |
bsm-62752r-100ul |
HMGCL Monoclonal Antibody |
WB, IHC-P, IHC-F, IF |
Human |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human HMGCL |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
3155 |
P35914 |
Cytoplasm |
HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725. |
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. |
Application Dilution |
WB |
:1:1000-1:2000 |
IHC-P |
IHC-P:1:100-1:200 |
IHC-F |
IHC-F:1:100-1:200 |
IF |
IF:1:100-1:200 |