Overview |
bsm-62733r-hrp-100ul |
CLIC4 Recombinant Monoclonal Antibody, HRP Conjugated |
WB, IHC-P, IHC-F |
Human, Mouse, Rat |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human CLIC4 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
25932 |
Q9Y696 |
Cytoplasm, Nucleus, Cell membrane |
Chloride intracellular channel 4; Clic4; CLIC4L; HUH1; MC3S5; mtCLIC; p64H1. |
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |