Overview |
bsm-62610r-100ul |
TORC2 Monoclonal Antibody |
WB, IHC-P, IHC-F, IF |
Human |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human CRTC2 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
200186 |
Q53ET0 |
Cytoplasm, Nucleus |
CRTC2; torc2; Transducer of CREB protein 2. |
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. |
Application Dilution |
WB |
:1:1000-1:2000 |
IHC-P |
IHC-P:1:100-1:200 |
IHC-F |
IHC-F:1:100-1:200 |
IF |
IF:1:100-1:200 |