| Overview |
| bsm-62610r-100ul |
| TORC2 Recombinant Antibody |
| WB, IHC-P, IHC-F, IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CRTC2 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 200186 |
| Q53ET0 |
| Cytoplasm, Nucleus |
| CRTC2; torc2; Transducer of CREB protein 2. |
| Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF |
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