Thrombomodulin Monoclonal Antibody

Overview
Catalog #	bsm-62575r-100ul
Product Name	Thrombomodulin Monoclonal Antibody
Applications	WB, FCM, IHC-P, IHC-F, IF
Reactivity	Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from mouse Thrombomodulin
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	21824
Swiss Prot	P15306
Subcellular location	Cell membrane
Synonyms	AHUS6; BDCA3; CD141; CD141 antigen; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin.
Background	Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Application Dilution
WB	:1:1000-1:2000
FCM	FCM:1:20-1:100
IHC-P	IHC-P:1:100-1:200
IHC-F	IHC-F:1:100-1:200
IF	IF:1:100-1:200