| Overview |
| bsm-62572r-100ul |
| RPS6KA3 Recombinant Antibody |
| WB, FCM, IHC-P, IHC-F, IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human p90 S6K alpha 3 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 6197 |
| P51812 |
| Cytoplasm, Nucleus |
| CLS; HU2; HU3; Insulin stimulated protein kinase 1; ISPK1; MAP kinase activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK 1b; MAPKAPK1B; MRX19; p90 RSK2; p90 RSK3; p90RSK3; pp90RSK2; Ribosomal protein S6 kinase alpha 3; Ribosomal protein s6 kinase ii alpha 2; Ribosomal S6 kinase 2; Rps6ka3; RSK; RSK2; S6 kinase 2; S6K alpha3. |
| Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF |
|
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