ABRAXAS1 Recombinant Monoclonal Antibody

Overview
Catalog #	bsm-62560r-100ul
Product Name	ABRAXAS1 Recombinant Monoclonal Antibody
Applications	WB, FCM, IF(ICC), IP
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human ABRAXAS1
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	Lot dependent
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	84142
Swiss Prot	Q6UWZ7
Subcellular location	Nucleus
Synonyms	ABRA1; ABRAXAS; FAM175A.
Background	Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.
Application Dilution
WB	1:300-5000
FCM	1:20-100
IF(ICC)	1:50-200
IP	1-2ug