Overview |
bsm-62482r-hrp-100ul |
OPG Recombinant Monoclonal Antibody, HRP Conjugated |
IHC-P, IHC-F |
Human |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human TNFRSF11B |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
4982 |
O00300 |
OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1. |
Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. |
Application Dilution |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |