THEMIS Recombinant Monoclonal Antibody

Overview
Catalog #	bsm-62442r-100ul
Product Name	THEMIS Recombinant Monoclonal Antibody
Applications	WB, FCM, IF(ICC), IP
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human THEMIS
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	Lot dependent
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	387357
Swiss Prot	Q8N1K5
Subcellular location	Cytoplasm, Nucleus
Synonyms	Protein THEMIS; SPOT; THEMIS; TSEPA.
Background	Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Application Dilution
WB	1:300-5000
FCM	1:20-100
IF(ICC)	1:50-200
IP	1-2ug