| Overview |
| bsm-62438r-biotin-100ul |
| RanBP3 Recombinant Monoclonal Antibody, Biotin Conjugated |
| WB, IHC-P, IHC-F, IP |
| Human, Mouse |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human RanBP3 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 8498 |
| Q9H6Z4 |
| Cytoplasm, Nucleus |
| Ran binding protein 3; RanBP3. |
| Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IP |
1-2ug |
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