Overview |
bsm-62393r-100ul |
ERCC8 Monoclonal Antibody |
WB, IP |
Human |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human ERCC8 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
1161 |
Q13216 |
Nucleus |
CKN1; CSA; ERCC8. |
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. |
Application Dilution |
WB |
:1:1000-1:2000 |
IP |
IP:1:20-1:50 |