Overview |
bsm-62389r-100ul |
PITX3 Monoclonal Antibody |
WB, FCM, IP |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human Pituitary homeobox 3 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
5309 |
O75364 |
Nucleus |
Pitx3; PTX3. |
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
Application Dilution |
WB |
:1:1000-1:2000 |
FCM |
FCM:1:20-1:100 |
IP |
IP:1:20-1:50 |