| Overview |
| bsm-62373r-bf647-100ul |
| DOK1 Recombinant Monoclonal Antibody, AbBy Fluor® 647 Conjugated |
| WB, IF(ICC) |
| Human, Mouse, Rat |
| Specifications |
| AbBy Fluor® 647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human DOK1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1796 |
| Q99704 |
| Cytoplasm |
| DOK1; p62(dok); P62DOK; pp62. |
| DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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