Overview |
bsm-62274r-apc-cy55-100ul |
PIAS2 Recombinant Monoclonal Antibody, APC-Cy5.5 Conjugated |
WB, IF(ICC) |
Human, Mouse, Rat |
Specifications |
APC-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human PIAS2 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
9063 |
O75928 |
DIP; MIZ; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIASX-BETA; PIASX-ALPHA. |
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |