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Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Monoclonal Antibody, AbBy Fluor® 750 Conjugated

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-62258r-bf750-100ul
Product Name Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Monoclonal Antibody, AbBy Fluor® 750 Conjugated
Applications WB, IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation AbBy Fluor® 750
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279
Modification Site Tyr279/Tyr216
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2931
Swiss Prot P49840
Subcellular location Cytoplasm
Synonyms Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A.
Background GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200