Overview |
bsm-62258r-bf750-100ul |
Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Monoclonal Antibody, AbBy Fluor® 750 Conjugated |
WB, IF(ICC) |
Human, Mouse, Rat |
Specifications |
AbBy Fluor® 750 |
Rabbit |
KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279 |
Tyr279/Tyr216 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2931 |
P49840 |
Cytoplasm |
Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A. |
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |