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VPS24 Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IP
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-62190r-100ul
Product Name VPS24 Monoclonal Antibody
Applications WB, FCM, IHC-P, IHC-F, IP, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human VPS24
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 51652
Swiss Prot Q9Y3E7
Subcellular location Cytoplasm, Cell membrane
Synonyms VPS24; CGI149; CHMP3; hVps24; NEDF.
Background Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.
Application Dilution
WB :1:1000-1:2000
FCM FCM:1:20-1:100
IHC-P IHC-P:1:100-1:200
IHC-F IHC-F:1:100-1:200
IP IP:1:20-1:50
IF IF:1:100-1:200