Overview |
bsm-62174r-percp-cy7-100ul |
TMPRSS2 Recombinant Monoclonal Antibody, PerCP-Cy7 Conjugated |
WB, FCM, IF(ICC) |
Human, Mouse, Rat |
Specifications |
PerCP-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human TMPRSS2 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
7113 |
O15393 |
Secreted, Cell membrane |
Epitheliasin; PRSS10; TMPRSS2. |
Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.(Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |