PAF1 Monoclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bsm-62168r-100ul |
Product Name | PAF1 Monoclonal Antibody |
Applications | WB |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human PAF1 |
Clonality | Monoclonal |
Clone # | Recombinant |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage Condition | Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 54623 |
Swiss Prot | Q8N7H5 |
Subcellular location | Nucleus |
Synonyms | hPAF1; PAF1; PD2. |
Background | Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. |
Application Dilution | |
WB | :1:1000-1:2000 |