Overview |
bsm-62128r-100ul |
DISC1 Recombinant Monoclonal Antibody |
WB, FCM, IHC-P, IHC-F, IF(ICC), IP, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human DISC1 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
27185 |
Q9NRI5 |
Cytoplasm, Cell membrane |
C1orf136; DISC1; KIAA0457; RP4-730B13.1; SCZD9. |
Involved in the regulation of multiple aspects of embryonic and adult neurogenesis.Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus.Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF(ICC) |
1:50-200 |
IP |
1-2ug |
IF |
|