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WAPL Recombinant Monoclonal Antibody

Applications

  • WB
  • IF(ICC)
  • IP

Reactivity

  • Human
Overview
Catalog # bsm-62097r-100ul
Product Name WAPL Recombinant Monoclonal Antibody
Applications WB, IF(ICC), IP
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human WAPL
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 23063
Swiss Prot Q7Z5K2
Subcellular location Cytoplasm, Nucleus
Synonyms FOE; WAPAL; WAPL; Wings apart like homolog.
Background Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin.Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200
IP 1-2ug