Overview |
bsm-62074r-100ul |
TINF2 Recombinant Antibody |
WB |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human TINF2 |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Target |
26277 |
Q9BSI4 |
DKCA3; Tin 2; TIN2; TINF 2; Tinf2. |
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. |
Application Dilution |
WB |
1:300-5000 |