| Overview |
| bsm-62028r-100ul |
| Niemann Pick C1 Like 1 Recombinant Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NPC1L1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 29881 |
| Q9UHC9 |
| Cell membrane |
| NPC1 LIKE 1; NPC1L1. |
| Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia. |
| Application Dilution |
| WB |
1:300-5000 |
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