Overview |
bsm-61980r-percp-cy7-100ul |
p53 DINP1 Recombinant Monoclonal Antibody, PerCP-Cy7 Conjugated |
WB, IF(ICC) |
Human, Mouse, Rat |
Specifications |
PerCP-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human p53 DINP1 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
94241 |
Q96A56 |
Cytoplasm, Nucleus |
p53DINP1; SIP; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B. |
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |