| Overview |
| bsm-61980r-apc-100ul |
| p53 DINP1 Recombinant Monoclonal Antibody, APC Conjugated |
| WB, IF(ICC) |
| Human, Mouse, Rat |
| Specifications |
| APC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human p53 DINP1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 94241 |
| Q96A56 |
| Cytoplasm, Nucleus |
| p53DINP1; SIP; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B. |
| Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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