Overview |
bsm-61945r-apc-cy5-100ul |
Exportin 5 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated |
WB, FCM, IF(ICC) |
Human, Mouse, Rat |
Specifications |
APC-Cy5 |
Rabbit |
KLH conjugated synthetic peptide derived from human Exportin 5 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
57510 |
Q9HAV4 |
Cytoplasm, Nucleus |
Exp5; Exportin 5; Ranbp21; xpo5. |
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |