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DARC Recombinant Monoclonal Antibody, AbBy Fluor® 647 Conjugated

Applications

  • WB
  • FCM
  • IF(ICC)

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-61907r-bf647-100ul
Product Name DARC Recombinant Monoclonal Antibody, AbBy Fluor® 647 Conjugated
Applications WB, FCM, IF(ICC)
Reactivity Human, Mouse
Specifications
Conjugation AbBy Fluor® 647
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2532
Swiss Prot Q16570
Subcellular location Cell membrane
Synonyms CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1.
Background Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200