Overview |
bsm-61907r-bf647-100ul |
DARC Recombinant Monoclonal Antibody, AbBy Fluor® 647 Conjugated |
WB, FCM, IF(ICC) |
Human, Mouse |
Specifications |
AbBy Fluor® 647 |
Rabbit |
KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2532 |
Q16570 |
Cell membrane |
CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1. |
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |