Overview |
bsm-61845r-cy3-100ul |
MMP17 Recombinant Monoclonal Antibody, Cy3 Conjugated |
WB, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human MMP17 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
4326 |
Q9ULZ9 |
Extracellular, Secreted, Cell membrane |
MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4. |
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |