| Overview |
| bsm-61838r-100ul |
| SMURF2 Monoclonal Antibody |
| WB |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human SMURF2 |
| Monoclonal |
| Recombinant |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 64750 |
| Q9HAU4 |
| Cytoplasm, Nucleus, Cell membrane |
| hSMURF2; SMUF2_HUMAN; Smurf2. |
| E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling. |
| Application Dilution |
| WB |
:1:1000-1:2000 |
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