Nkx3.1 Monoclonal Antibody

Overview
Catalog #	bsm-61752r-100ul
Product Name	Nkx3.1 Monoclonal Antibody
Applications	WB, IHC-P, IHC-F, IF
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human Nkx 3.1
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	4824
Swiss Prot	Q99801
Subcellular location	Nucleus
Synonyms	NKX3; BAPX2; NKX3A; NKX3.1; NKX3-1.
Background	Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Application Dilution
WB	:1:1000-1:2000
IHC-P	IHC-P:1:100-1:200
IHC-F	IHC-F:1:100-1:200
IF	IF:1:100-1:200