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SAMHD1/MOP5 Recombinant Monoclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-61737r-pe-100ul
Product Name SAMHD1/MOP5 Recombinant Monoclonal Antibody, PE Conjugated
Applications WB, FCM, IF(ICC)
Reactivity Human
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human SAMHD1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 25939
Swiss Prot Q9Y3Z3
Subcellular location Nucleus
Synonyms SAMHD1; AGS5; CHBL2; DCIP; HDDC1; MOP-5; MOP5; SBBI88; Mg11.
Background Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells .
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200