| Overview |
| bsm-61694r-rbitc-100ul |
| KSR1 Recombinant Monoclonal Antibody, RBITC Conjugated |
| WB, FCM, IF(ICC) |
| Human, Mouse |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human KSR1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8844 |
| Q8IVT5 |
| Cytoplasm, Cell membrane |
| BKSR1; dKsr; EK31; KSR; KSR1; RSU2; SR31. |
| Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases.Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IF(ICC) |
1:50-200 |
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