| Overview |
| bsm-61679r-bf405-100ul |
| TRPM7 Recombinant Monoclonal Antibody, AbBy Fluor® 405 Conjugated |
| WB, FCM, IF(ICC) |
| Human, Mouse, Rat |
| Specifications |
| AbBy Fluor® 405 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TRPM7 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 54822 |
| Q96QT4 |
| Cell membrane |
| ALSPDC; CHAK; CHAK1; LTrpC7; TRPM7. |
| Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium.Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IF(ICC) |
1:50-200 |
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