Overview |
bsm-61673r-100ul |
PAK2 Recombinant Monoclonal Antibody |
WB, FCM, IHC-P, IHC-F, IF(ICC), IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human PAK2 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
5062 |
Q13177 |
Cytoplasm |
CB422; Gamma PAK; hPAK65; p27; p34; p58; p65PAK; PAK-2p34; Pak2; PAK65; PAKgamma; S6 H4 kinase. |
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation.Acts as a downstream effector of the small GTPases CDC42 and RAC1.Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF(ICC) |
1:50-200 |
IF |
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