Overview |
bsm-61659r-100ul |
TAX1BP3 Monoclonal Antibody |
WB, FCM, IHC-P, IHC-F, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human Tax1 binding protein 3 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
30851 |
O14907 |
Cytoplasm, Nucleus |
Glutaminase interacting protein 3; Tax interaction protein 1; Tax1 binding protein 3; Tax1bp3; TIP1. |
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. |
Application Dilution |
WB |
:1:1000-1:2000 |
FCM |
FCM:1:20-1:100 |
IHC-P |
IHC-P:1:100-1:200 |
IHC-F |
IHC-F:1:100-1:200 |
IF |
IF:1:100-1:200 |