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HP1 gamma Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IP
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61603r-100ul
Product Name HP1 gamma Monoclonal Antibody
Applications WB, FCM, IHC-P, IHC-F, IP, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CBX3
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 11335
Swiss Prot Q13185
Subcellular location Nucleus
Synonyms Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein; CBX3; HP1 gamma.
Background Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Application Dilution
WB :1:1000-1:2000
FCM FCM:1:20-1:100
IHC-P IHC-P:1:100-1:200
IHC-F IHC-F:1:100-1:200
IP IP:1:20-1:50
IF IF:1:100-1:200