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CENPE Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-61569r-100ul
Product Name CENPE Monoclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CENPE
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 1062
Swiss Prot Q02224
Subcellular location Nucleus
Synonyms CENP E; Centromere associated protein E; Centromere protein E 312kDa; KIF10; Kinesin family member 10; Kinesin related protein; PPP1R61.
Background Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly checkpoint activation. Drives chromosome congression (alignment of chromosomes at the spindle equator resulting in the formation of the metaphase plate) by mediating the lateral sliding of polar chromosomes along spindle microtubules towards the spindle equator and by aiding the establishment and maintenance of connections between kinetochores and spindle microtubules.
Application Dilution
WB :1:1000-1:2000