FRS2 Monoclonal Antibody

Overview
Catalog #	bsm-61526r-100ul
Product Name	FRS2 Monoclonal Antibody
Applications	WB, FCM, IP
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human FGFR substrate 2
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	10818
Swiss Prot	Q8WU20
Subcellular location	Cytoplasm, Cell membrane
Synonyms	FGFR signaling adaptor SNT; FGFR substrate 2; FRS2; FRS2A; FRS2 alpha; SNT; SNT1; Suc 1.
Background	Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Application Dilution
WB	:1:1000-1:2000
FCM	FCM:1:20-1:100
IP	IP:1:20-1:50