| Overview |
| bsm-61496r-100ul |
| DR5 Monoclonal Antibody |
| WB, FCM, IP |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human DR5 |
| Monoclonal |
| Recombinant |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 8795 |
| O14763 |
| Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9. |
| Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
| Application Dilution |
| WB |
:1:1000-1:2000 |
| FCM |
FCM:1:20-1:100 |
| IP |
IP:1:20-1:50 |
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