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Profilin 1 Recombinant Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IF(ICC)
  • IP
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61480r-100ul
Product Name Profilin 1 Recombinant Monoclonal Antibody
Applications WB, FCM, IHC-P, IHC-F, IF(ICC), IP, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Profilin 1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 5216
Swiss Prot P07737
Subcellular location Cytoplasm
Synonyms Actin binding protein; ALS18; Epididymis tissue protein Li 184a; PFN 1; Pfn; PFN1; Profilin1; ProfilinI.
Background Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200
IP 1-2ug
IF